constipation

Constipation: Causes, Symptoms, and Relief

About 16 out of 100 U.S. adults deal with constipation1. This issue can cause a lot of discomfort and frustration. But, knowing what causes it, what symptoms to watch for, and how to find relief can help people get their digestive health back on track.

Constipation means you don’t have bowel movements often or they’re hard. You might also have hard, lumpy stools, feel like you’re straining, or feel like you didn’t fully go to the bathroom2. It might seem like a small problem, but it can really affect your life and health if you don’t deal with it.

Looking into what causes constipation, spotting the signs, and trying different ways to feel better can help. This way, people can take steps to fix this issue and keep their digestive system healthy.

Key Takeaways

  • Constipation is a common issue affecting about 16 out of 100 U.S. adults1.
  • Things like lifestyle, some medicines, and health conditions can cause constipation.
  • Symptoms include not going to the bathroom often, having hard or lumpy stools, and feeling like you didn’t fully go.
  • Relief can come from changing your diet and lifestyle, using over-the-counter laxatives, or sometimes prescription drugs or medical help.
  • Eating a lot of fiber, drinking plenty of water, and exercising regularly can help prevent and fix constipation.

What is Constipation?

Definition and Overview

Constipation means having trouble or not going to the bathroom often3. The Mayo Clinic says it’s when you go to the bathroom less than three times a week or it’s hard3. It’s a common issue caused by diet changes, not moving enough, some medicines, and health problems.

Over 4 million Americans deal with constipation regularly3. Women get it more often than men3. It’s when you have less than three bowel movements a week, and your stools are hard, dry, and small3. Some people go more often, while others less often3.

To fight constipation, slowly add more fiber until you get 20 to 35 grams a day3. Drinking at least 8 glasses of water a day is also key3. Coffee can help too, thanks to its caffeine3. But, eating cheese, processed foods, and high-fat/low-fiber foods can make it worse3.

Prebiotics and probiotics can help your gut bacteria, which might ease constipation3. Use laxatives only after trying more fiber and water, and don’t use them for a long time3. There are different laxatives like fiber supplements, lubricants, osmotic laxatives, stimulants, and stool softeners3. If over-the-counter treatments don’t work, your doctor might suggest stronger ones like linaclotide, lubiprostone, and plecanatide3.

Symptoms of Constipation

Common Signs

Constipation is quite common4. It shows up when you have fewer than three bowel movements a week. You might also have hard or lumpy stools, feel like you’re not fully done after going to the bathroom, or feel like your rectum is blocked5. Other signs include feeling bloated, having cramps, and needing to use your fingers to help with bowel movements5.

If you have these symptoms for three months or more, you might have chronic constipation4. This needs a doctor’s help.

About 4 million people in the U.S. deal with constipation often6. It leads to 2.5 million doctor visits a year in the U.S6. Being older, a woman, not active, or having mental health issues can make constipation worse4. Long-term constipation can cause problems like hemorrhoids, anal fissures, fecal impaction, or rectal prolapse4.

If your constipation doesn’t get better with home remedies or you have a family history of colon or rectal cancer, see a doctor5. You should get help right away if you have bleeding, blood in your stool, constant belly pain, trouble passing gas, vomiting, fever, or lower back pain5.

To avoid constipation, eat foods high in fiber, drink lots of water, stay active, and don’t ignore the urge to go to the bathroom4. Foods like whole wheat bread, granola bread, and cereals like All-Bran are good for fiber6. Vegetables and fruits such as beets, broccoli, and berries are also great sources6.

Symptom Description
Fewer than 3 bowel movements per week Infrequent bowel movements can be a sign of constipation.
Hard, dry, or lumpy stools Stool that is difficult to pass can indicate constipation.
Straining or pain when passing stool Difficulty and discomfort during bowel movements can be a symptom of constipation.
Feeling of incomplete evacuation A sensation that not all stool has been passed can be a sign of constipation.
Sensation of blocked or obstructed rectum Feeling of a blocked or obstructed rectum can indicate constipation.

In summary, constipation signs include not going to the bathroom often, having hard stools, straining, feeling not fully emptied, and feeling blocked. If it lasts three months or more, you should see a doctor. To prevent it, eat fiber-rich foods, drink plenty of water, exercise, and have a regular bowel routine465.

Causes of Constipation

Lifestyle Factors

Constipation is a common issue that often comes from our daily habits and choices7. A big cause is not getting enough dietary fiber, which is key for regular bowel movements. Eating lots of processed foods, fatty meats, dairy, and sweets can make constipation worse. But, eating foods high in fiber like whole grains, veggies, fruits, and beans can help8.

Not drinking enough fluids, like water, is another big cause of constipation7. Hard stools make it tough to go to the bathroom. Sitting too much and not moving around can also make constipation more likely. Exercise helps keep the digestive system working right78.

Some medicines, like opioid painkillers, antidepressants, and certain blood pressure drugs, can cause constipation79. Also, ignoring the need to go to the bathroom, often because you’re busy or away from home, can lead to constipation8.

While lifestyle plays a big part in constipation, some health issues like irritable bowel syndrome, thyroid problems, or gut problems might need a doctor’s help89. By changing our lifestyle, we can often ease constipation and boost our gut health.

“Constipation is a common problem that can be managed through simple lifestyle changes, such as increasing fiber intake, staying hydrated, and engaging in regular physical activity.”

Lifestyle Factor Impact on Constipation
Dietary Fiber Inadequate fiber intake can lead to constipation789.
Fluid Intake Dehydration can contribute to harder stools and constipation78.
Physical Activity Lack of exercise can increase the risk of constipation78.
Medication Side Effects Certain medications, such as opioids and antidepressants, can cause constipation79.
Ignoring Bowel Urges Putting off bowel movements can contribute to constipation8.

789

Medications and Constipation

Some medications can make constipation worse as a side effect10. Opioid painkillers slow down the intestines, making it hard to pass stool10. Iron supplements, antidepressants, blood pressure meds, and nausea drugs can also cause constipation because they slow down bowel movements.

The Mayo Clinic lists many medications that can cause constipation11. These include drugs for high blood pressure, seizures, depression, and allergies, as well as some antacids. Even some over-the-counter supplements like iron can cause constipation. People taking these medications should talk to their doctor about constipation risks.

Stimulant laxatives like sennosides are often the first choice because they are mild and work well12. For those with bowel cramps, osmotic laxatives like polyethylene glycol (PEG) are recommended12.

It’s important to adjust laxative doses based on your own bowel habits and goals, known as a protocol12. Most people find the sennosides protocol easier than PEG. Start with either sennosides or PEG, but not both at once12.

Move up the protocol every 24 hours until you have a regular bowel movement12. If you get diarrhea, stop taking laxatives until you have a normal bowel movement, then start again at a lower step12. If you have severe stomach cramps, stop taking sennosides and call a doctor12.

If the constipation doesn’t get better, you might need lactulose syrup12. Always ask for medical advice if you’re unsure about laxative dosage or if constipation lasts even after reaching the highest step12. Don’t take diarrhea medicine if you have watery stools after constipation12.

Everyone taking medications should know about the risk of constipation and talk to their healthcare providers to manage it well.

Medical Conditions and Constipation

Constipation can be caused by many medical conditions that affect the digestive system or the nerves and muscles that help with bowel movements13. These include irritable bowel syndrome, diabetes, multiple sclerosis, Parkinson’s disease, hypothyroidism, and problems with the pelvic floor muscles13. Sometimes, blockages in the colon or rectum, like tumors or structural changes, can also cause constipation14. Finding the root cause of constipation can be hard.

Underlying Health Issues

Constipation is a common problem that can get worse with various medical conditions15. Around 15% of people worldwide have chronic constipation14. Some diseases and conditions, like colon cancer, inflammatory bowel disease (IBD), megacolon, and rectal prolapse, are linked to constipation14. Also, research shows that people with chronic constipation often have mental health issues like anxiety, depression, and eating disorders14.

Some medicines can also make constipation worse1415. Antacids, antidepressants, antiepileptics, antihistamines, antipsychotics, and muscle relaxants are common culprits1415. Conditions like diabetes and Parkinson’s disease can also cause constipation14.

Medical Condition Impact on Constipation
Irritable Bowel Syndrome (IBS) More than one-third of individuals with IBS have constipation-predominant IBS (IBS-C)14.
Diabetes Approximately 60% of people with long-standing diabetes experience constipation14.
Multiple Sclerosis Nerve damage from this condition can disrupt normal bowel function and lead to constipation.
Parkinson’s Disease The disease can affect the nerves and muscles involved in the digestive process, contributing to constipation.
Hypothyroidism Slow thyroid function can slow down the digestive system and cause constipation.
Pelvic Floor Disorders Problems with the muscles and nerves that control bowel movements can result in constipation.

It’s important to address the underlying medical conditions that can cause constipation for better management and prevention14. Seeing a healthcare professional is a good idea to find and treat any health issues that might be causing or making constipation worse14.

“Constipation is a common issue that can be exacerbated by various medical conditions. Addressing the underlying medical conditions that can contribute to constipation is crucial for effective management and prevention.”

Risk Factors for Constipation

Constipation is a common issue that can affect anyone. But, some things make it more likely to happen16. The Mayo Clinic says some big risk factors are:

  • Being an older adult16
  • Being assigned female at birth, especially during pregnancy16
  • Living a life that’s mostly sitting down16
  • Having mental health issues like depression or eating disorders16
  • Eating too little fiber16

Some medicines and certain diseases can also make constipation worse16.

Constipation affects different people in different ways17. It’s found in 0.7% to 79% of people, but more in older folks and women17. In the U.S., about one in five folks deal with it18.

Knowing what makes constipation more likely helps us fight it18. By eating more fiber, drinking water, and moving more, we can lower our risk18.

risk factors for constipation

“Constipation is a big problem that can really change how we feel. By knowing the risks and acting early, we can keep our digestive health in check and dodge the bad parts of constipation.”

Complications of Chronic Constipation

Chronic constipation can lead to serious issues if not treated19. Hemorrhoids affect up to 4% of people and are more common in those over 4519. Anal fissures, small tears, can happen from hard stools or straining, especially in children who fear pain19.

Fecal impaction, a blockage in the intestines, is more common in kids and the elderly19. Chronic constipation can also cause rectal prolapse, needing medical help19.

Chronic constipation greatly affects quality of life, causing discomfort and pain20. Getting medical help and using the right treatments is key to avoid these issues and keep digestive health good20.

Up to 33% of adults over 60 suffer from chronic constipation21. About 49% of fecal impaction cases are due to chronic constipation21. Prolonged constipation raises the risk of hemorrhoids and anal fissures, causing pain21.

Not treating chronic constipation can lead to serious issues like fecal impaction, which can be dangerous21. It’s vital to see a doctor and follow a treatment plan to prevent these problems21.

“Chronic constipation is a common issue with serious consequences if ignored. Getting medical help and a specific treatment plan is key to stop complications and keep digestive health in check.”

Understanding the risks of chronic constipation and getting medical care quickly helps manage the condition and improve life quality20. With the right treatments, many complications can be prevented or reduced20.

Diagnosis of Constipation

Healthcare providers start by taking a detailed medical history and doing a physical exam. This may include a rectal exam to check for blockages22. They might order more tests to find out what’s causing constipation.

Tests and Evaluations

There are many tests to check for constipation, such as:

  • Blood tests: These show signs of anemia, hypothyroidism, and celiac disease23.
  • Stool tests: These look for blood and signs of infection and inflammation23.
  • Urine tests: These can show signs of diseases like diabetes23.
  • Radiopaque markers: An x-ray tracks these markers through the digestive system, taking about 3 to 7 days23.
  • Scintigraphy: This test uses a meal with a small dose of a radioactive substance, tracked by computers and cameras23.
  • Defecography: An x-ray of the anus and rectum to see how stool is held and released23.
  • Anorectal manometry: This checks how the rectum and anal sphincter work23.
  • Balloon expulsion test: This test sees if you can push out stool23.
  • Imaging tests: These include x-rays, MRI, and CT scans to find other problems causing constipation23.

These tests help doctors figure out why someone has constipation and plan the right treatment232422.

“Determining the underlying cause of constipation is crucial for effective management and relief of symptoms.”

By knowing what causes constipation in someone, doctors can make a treatment plan that really works232422.

Treatment for Constipation

Lifestyle Modifications

Many people can manage constipation by changing their lifestyle. Drinking more water is a key suggestion25. Eating foods high in fiber, like fruits and whole grains, can also help25. Regular exercise is another important step for healthy bowel movements25.

Having a regular bathroom routine and not ignoring the urge to go can help with constipation relief25. Cutting down on processed foods, dairy, and caffeine can also help25. For some, over-the-counter fiber supplements might be useful too25.

Eating more fiber is advised to help with constipation26. Foods like veggies, fruits, and whole grains can boost digestive health26. Regular exercise is also good for bowel movements, making the digestive system work better26.

In some cases, biofeedback training can be helpful for constipation caused by muscle issues26.

“Making lifestyle changes, such as increasing fiber intake and staying hydrated, can go a long way in relieving constipation for many people.”

Often, a mix of diet changes, exercise, and sometimes medical help is needed to manage constipation well252627.

Laxatives and Constipation

If changing your lifestyle doesn’t help, over-the-counter laxatives might be a good choice. There are many types, like fiber supplements, osmotic agents, and stimulant laxatives28. Always talk to a doctor to find the right one for you and how long to use it.

Fiber supplements, such as Metamucil and Citrucel, are gentle and help by making stool soft and bulky28. Adults need 25 to 31 grams of fiber daily to fight constipation28. Osmotic laxatives, like MiraLAX, can cause bloating and diarrhea28. Stimulant laxatives, including Dulcolax, make your intestines contract and may lead to cramping and diarrhea28.

Using laxatives for too long can harm your body, causing problems like heart rhythm issues and seizures28. Some laxatives mix different types, but they might not work better and could cause more side effects28. They can also interact with other medicines, making it harder to find the right one28.

Using laxatives too much can make constipation worse by weakening your colon’s muscles28. Pregnant women and those breastfeeding should talk to a doctor before taking laxatives, as some can be harmful28.

Laxative Type Onset of Action Potential Side Effects
Bulk-forming 12-24 hours29 Bloating, flatulence
Osmotic 2-3 days29 Bloating, cramping, diarrhea
Stimulant 6-12 hours29 Cramping, belching, diarrhea
Stool softener 12-72 hours29 Mild discomfort
Lubricant Variable Mineral oil can reduce absorption of fat-soluble vitamins30

Be careful with laxatives and always talk to a doctor. Using them too much can cause serious problems like dehydration and addiction29. Trying natural ways, like eating more fiber and drinking water, can also help with constipation29.

In summary, laxatives can help with constipation, but use them wisely and talk to a doctor. Choosing the right laxative, the right amount, and for the right time can help you feel better safely282930.

Prescription Medications for Constipation

For those with chronic or severe constipation, prescription drugs might help. These drugs can ease symptoms when over-the-counter options don’t work well. Studies show that many people suffer from constipation31. Prescription meds can be key for those whose quality of life is affected by bowel issues31.

Common prescription options include lubiprostone (Amitiza), linaclotide (Linzess), lactulose, plecanatide (Trulance), and prucalopride (Motegrity). Research shows these drugs help with constipation32. They have been shown to work well and are easy to tolerate32.

For constipation caused by opioid pain meds, there are special prescription drugs. Options like methylnaltrexone (Relistor), naldemedine (Symproic), and naloxegol (Movantik) can help. Around 41 to 81 percent of people on opioids for noncancer pain get constipated33. These targeted treatments are crucial for them.

Choosing the right prescription medication for constipation means working with a healthcare provider. They will consider your medical history, current conditions, and how you’ve reacted to other treatments. It might take some trial and error to find the best option and manage any side effects.

“Prescription medications can be a game-changer for those with chronic or severe constipation, providing relief when other methods fall short.”

Surgical Interventions for Constipation

Surgery is not often used to treat constipation. But, it might be needed for some to fix serious problems. This includes fixing anal tears, removing blockages, or treating rectal prolapse34. The goal is to fix the body’s structure and help the digestive system work better. Surgery is usually a last resort when other treatments don’t work.

A surgery called a total abdominal colectomy with ileorectal anastomosis (TAC IRA) can help with chronic constipation. It removes the whole colon and connects the small intestine to the rectum. This surgery has been successful for over 90% of people, making them have 1 to 3 bowel movements daily34. A survey showed that 93% of patients would choose this surgery again if they could34.

Another surgery for constipation is taking out part of the colon. But, this might lead to needing more surgery in up to 50% of cases34. On the other hand, the success rate for TAC IRS is over 90%, with different ways to measure success34.

It’s key to know that surgery can help some people, but it’s very safe for healthy patients, with a death rate less than 1%34. Yet, some people might face complications like small bowel obstruction or ongoing pain after surgery34.

When thinking about surgery for constipation, it should be a last choice. Make sure other treatments have been tried first. Always talk to a healthcare expert to see if surgery is right for you.

surgery for constipation

“Surgery is typically reserved for cases where other treatment methods have been unsuccessful.”

Prevention of Constipation

Lifestyle Changes

Preventing constipation starts with simple changes in your daily life. Eating foods high in fiber like fruits, veggies, and whole grains is key35. Aim for 25–30 grams of fiber a day if you’re a woman, and 30–38 grams if you’re a man35. Prunes and prune juice are great for constipation relief because they’re full of fiber and sorbitol35. Drinking enough water is also vital, as not staying hydrated can lead to constipation36.

Being active helps keep your bowels moving smoothly and prevents constipation36. Having a regular bathroom routine is also important, listening to your body’s signals to go37. But, eating too much fat or following a high-fat diet can make constipation worse35. The BRAT diet, with bananas, rice, applesauce, and toast, is good for digestive issues like constipation35.

Sticking to regular meal times can help keep your bowels regular by keeping your digestive system active35. But, how fasting affects bowel movements can differ based on the fasting plan you follow35. Supplements like psyllium husks or guar gum can help with constipation, but only use them as directed35.

By making these lifestyle changes, you can take steps to

Constipation in Specific Populations

Constipation is a big issue for some groups of people. This includes older adults, women, especially during pregnancy, and those with mental health issues like depression or eating disorders38. These groups face a higher risk of constipation due to slower metabolism, hormonal changes, less physical activity, and certain medications38. They need special care to manage their constipation.

For older adults, constipation affects 24% to 30% in the U.S39. It’s more common in women than men and gets worse with age40. Helping older people with constipation means looking at many things like how active they are, their meds, and what they eat.

Pregnant women also struggle with constipation a lot40. Hormonal shifts, less activity, and the growing baby can cause it. Eating well, drinking plenty of water, and doing gentle exercises can help.

People with mental health issues like depression or eating disorders often get constipation too38. The mix of mental health, meds, and gut issues can make constipation a long-term problem. Treating the mental health and using laxatives or diet changes can help.

It’s important to understand the special challenges of constipation in these groups. By knowing how constipation affects older adults, pregnant women, and those with mental health issues, doctors can give better care. This can make a big difference in their lives384039.

Conclusion

Constipation is a common issue that can come from many things like our lifestyle, some medicines, and health problems41. It can make life tough with symptoms like not going to the bathroom often, hard stools, and feeling like you didn’t finish going to the bathroom42. Luckily, it can often be fixed with simple changes in diet and lifestyle, or with medicines you can buy over the counter or by prescription. But sometimes, you might need more help or even surgery.

Not everyone gets constipation, but it’s pretty common, affecting 2% to 30% of people, and up to 75% of older folks in care homes43. Things like taking certain medicines, having health issues, and how you live can make you more likely to get it41. Knowing what causes it, what it feels like, and how to treat it can help you stop it and manage it better. This can make your digestive health and overall well-being much better.

This article has given a full summary of constipation, covering what causes it, what it feels like, and how to handle it. With this info, readers can understand and tackle this common digestive problem better. This can lead to better health and a better life overall.

FAQ

What is constipation?

Constipation means you don’t have regular or easy bowel movements. It can happen for many reasons, like diet changes, not moving much, some medicines, or health issues.

What are the symptoms of constipation?

Signs of constipation include fewer than three bowel movements a week. You might also have hard or lumpy stools, struggle to pass stool, or feel like you didn’t fully go to the bathroom.

What can cause constipation?

Many things can cause constipation. This includes your lifestyle, like diet and exercise habits, and some medicines. Health conditions like irritable bowel syndrome, diabetes, and some nerve disorders can also cause it.

How can medications contribute to constipation?

Some medicines can make you constipated. This includes painkillers, blood pressure drugs, seizure medications, antidepressants, and certain antacids with calcium or aluminum.

What medical conditions can lead to constipation?

Certain health issues can make you constipated. These include irritable bowel syndrome, diabetes, multiple sclerosis, Parkinson’s disease, hypothyroidism, and problems with the muscles in your pelvic area.

Who is at higher risk of developing constipation?

Some people are more likely to get constipated. This includes older adults, women, especially during pregnancy, people who don’t move much, those with mental health issues, and those eating too little fiber.

What are the potential complications of chronic constipation?

Not treating constipation can lead to serious problems. These include hemorrhoids, anal fissures, fecal impaction, and rectal prolapse.

How is constipation diagnosed?

Doctors diagnose constipation by talking to you, doing a physical check-up, and sometimes running tests. They might ask for blood, stool, or imaging tests to find the cause.

What are some lifestyle modifications for managing constipation?

To help with constipation, try eating more fiber, drinking plenty of water, being active, and going to the bathroom at the same time every day.

When are laxatives used to treat constipation?

If changing your diet and lifestyle doesn’t help, doctors might suggest laxatives. These can be over-the-counter or prescription drugs, like fiber supplements or stool softeners.

What prescription medications are used to treat chronic constipation?

For ongoing constipation, doctors might prescribe stronger medicines. These include lubiprostone, linaclotide, lactulose, plecanatide, and prucalopride.

When is surgery considered for constipation?

Surgery is rare for constipation but needed for some serious issues. This includes fixing anal tears, removing blockages, or treating rectal prolapse.

How can constipation be prevented?

To avoid constipation, eat lots of fiber, drink water, exercise regularly, and have a regular bathroom routine.

Are there any unique challenges in managing constipation for specific populations?

Some groups, like older adults, pregnant women, and those with mental health issues, face special challenges with constipation. This can be due to slower metabolism, hormonal changes, or certain medicines.

Source Links

  1. Constipation: Symptoms, Causes, Relief, and More – https://www.healthline.com/health/constipation
  2. The Basics of Constipation – https://www.webmd.com/digestive-disorders/digestive-diseases-constipation
  3. Constipation Relief Guide – https://www.webmd.com/digestive-disorders/constipation-relief-tips
  4. Constipation – Symptoms and causes – https://www.mayoclinic.org/diseases-conditions/constipation/symptoms-causes/syc-20354253
  5. Symptoms & Causes of Constipation – NIDDK – https://www.niddk.nih.gov/health-information/digestive-diseases/constipation/symptoms-causes
  6. Constipation – https://www.hopkinsmedicine.org/health/conditions-and-diseases/constipation
  7. Concerned About Constipation? – https://www.nia.nih.gov/health/constipation/concerned-about-constipation
  8. Constipation | Cedars-Sinai – https://www.cedars-sinai.org/health-library/diseases-and-conditions/c/constipation.html
  9. Constipation – https://www.nhs.uk/conditions/constipation/
  10. 8 Types of Medication That Can Cause Constipation – GoodRx – https://www.goodrx.com/conditions/constipation/the-big-8-constipation-causing-medications
  11. Medicine to Treat Constipation – https://www.webmd.com/digestive-disorders/prescription-medications-to-treat-constipation
  12. How to Treat Constipation Caused by Your Medications – http://www.bccancer.bc.ca/health-info/coping-with-cancer/managing-symptoms-side-effects/constipation-caused-by-your-medications
  13. Constipation symptoms and treatments – https://www.nhsinform.scot/illnesses-and-conditions/stomach-liver-and-gastrointestinal-tract/constipation/
  14. Chronic Constipation: 5 Related Health Conditions – https://www.healthline.com/health/chronic-constipation/chronic-constipation-related-health-conditions
  15. Constipation – https://www.ucsfhealth.org/conditions/constipation
  16. The Most Likely Causes of Your Constipation – https://www.verywellhealth.com/constipation-causes-1944788
  17. Potential risk factors for constipation in the community – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8173388/
  18. Constipation: Causes and Prevention Tips – https://www.hopkinsmedicine.org/health/conditions-and-diseases/constipation-causes-and-prevention-tips
  19. How Chronic Constipation Affects Your Body – https://www.webmd.com/digestive-disorders/chronic-constipation-affects-body
  20. Constipation might be serious. It should not be left untreated. | Bangkok Hospital – https://www.bangkokhospital.com/en/content/constipation
  21. 3 Complications of Chronic Constipation: Atlantic Medical Group: Gastroenterologists – https://www.amg-gi.com/blog/3-complications-of-chronic-constipation
  22. Diagnostic Approach to Chronic Constipation in Adults – https://www.aafp.org/pubs/afp/issues/2011/0801/p299.html
  23. Diagnosis of Constipation – NIDDK – https://www.niddk.nih.gov/health-information/digestive-diseases/constipation/diagnosis
  24. Constipation – Diagnosis and treatment – Mayo Clinic – https://www.mayoclinic.org/diseases-conditions/constipation/diagnosis-treatment/drc-20354259
  25. Treatment for Constipation – NIDDK – https://www.niddk.nih.gov/health-information/digestive-diseases/constipation/treatment
  26. Chronic Constipation: Treatment Options – https://www.webmd.com/digestive-disorders/chronic-constipation-treatment
  27. Approach Considerations, Dietary Measures, Pharmacologic Therapy – https://emedicine.medscape.com/article/184704-treatment
  28. Nonprescription laxatives for constipation: Use with caution – https://www.mayoclinic.org/diseases-conditions/constipation/in-depth/laxatives/art-20045906
  29. Laxatives for constipation: Types, side effects, and misuse – https://www.medicalnewstoday.com/articles/10279
  30. How to Safely Use Laxatives for Constipation – https://www.webmd.com/digestive-disorders/laxatives-for-constipation-using-them-safely
  31. Treatment of Chronic Constipation: Prescription Medications and Surgical Therapies – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836568/
  32. Laxatives, Bulk-Producing, Laxatives, Stool Softener, Laxative, Stimulant; Laxative, Stool Softener, Laxatives, Saline, Laxatives, Lubricant, Laxatives, Other, Laxatives, Osmotic, Stimulant Laxatives, Prokinetic Agents, Peripherally-Acting Mu-Opioid Receptor Antagonists – https://emedicine.medscape.com/article/184704-medication
  33. Opioid-Induced Constipation – https://www.healthline.com/health/opioid-induced-constipation
  34. Surgical Management of Constipation – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780139/
  35. Foods for Constipation – https://www.hopkinsmedicine.org/health/wellness-and-prevention/foods-for-constipation
  36. Constipation – https://www.mountsinai.org/health-library/condition/constipation
  37. Constipation – https://www.healthdirect.gov.au/constipation
  38. Constipation: Evaluation and Management – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140151/
  39. Constipation: Practice Essentials, Background, Pathophysiology – https://emedicine.medscape.com/article/184704-overview
  40. Constipation – StatPearls – NCBI Bookshelf – https://www.ncbi.nlm.nih.gov/books/NBK513291/
  41. Constipation : Symptoms Causes and Remedies – https://medicahospitals.in/blog/constipation-can-be-cured/
  42. Functional Constipation – an overview – https://www.sciencedirect.com/topics/medicine-and-dentistry/functional-constipation
  43. Constipation – https://en.wikipedia.org/wiki/Constipation