Parkinson’s disease affects over 1 million Americans, making it a major health issue1. It’s a neurological disorder that takes away a person’s control over their movements1. It usually starts in middle or late life and is more common in men than women1. It’s rare in young adults1. The exact causes are still a mystery, but genetics and environment likely play a part2.
There’s no cure for Parkinson’s, but treatments like medications, surgery, and therapy can help manage symptoms3. These treatments can make life better for those with the disease. Understanding Parkinson’s and its effects is key to getting the right treatment.
Key Takeaways
- Parkinson’s disease is a progressive neurological disorder that primarily affects movement and motor function.
- Symptoms include tremors, slowed movement, muscle stiffness, impaired balance, and changes in speech and writing.
- The cause of Parkinson’s is not fully understood, but it is believed to involve a combination of genetic and environmental factors.
- While Parkinson’s cannot be cured, various medications, surgical interventions, and rehabilitation therapies can help manage the symptoms.
- Ongoing research is exploring new treatment approaches, including stem cell transplants and gene therapies.
Understanding Parkinson’s Disease
Parkinson’s disease is a complex and progressive neurological disorder. It mainly affects nerve cells in the brain. The breakdown and death of certain nerve cells, especially those making dopamine, cause it4. As dopamine levels drop, symptoms like tremors, slow movements, and muscle stiffness appear.
What is Parkinson’s Disease?
Parkinson’s disease is a chronic and progressive disorder that affects the central nervous system. It’s a movement disorder that impacts how one controls their movements and coordination5. It was named after James Parkinson, an English doctor who first described it in 1817.
This disease is marked by the loss of nerve cells in the brain’s substantia nigra that produce dopamine4. Losing these dopamine cells, which help with movement and coordination, causes the disease’s symptoms.
| Statistic | Value |
|---|---|
| Estimated people with Parkinson’s in the U.S. | 1 million5 |
| Estimated people with Parkinson’s worldwide | Over 10 million5 |
| Percentage of Parkinson’s diagnoses before age 50 | Approximately 10%5 |
| Parkinson’s disease affects more | Men than women6 |
| Average age of Parkinson’s onset | Around 70 years6 |
| Percentage with a known relative with Parkinson’s | 15 to 25%6 |
| Increased risk from pesticide exposure | Especially in rural areas6 |
Parkinson’s disease gets worse over time, meaning its symptoms will worsen4. There is no cure, but treatments can help manage symptoms and improve life quality for those with the disease.
“Parkinson’s disease is the 14th cause of death in the U.S. based on data from the Centers for Disease Control and Prevention (CDC).”4
Understanding Parkinson’s disease, its causes, and treatment options is key for those with the disease and their caregivers. Being informed helps patients and their support networks face the challenges of this complex disorder.
Symptoms of Parkinson’s Disease
Parkinson’s disease brings many symptoms that can change daily life a lot. Key symptoms are tremors, bradykinesia (slow movement), muscle rigidity, and issues with posture and balance. Speech and writing also change78.
Tremors
Tremor is a big sign of Parkinson’s, starting often in the hand or arm7. It happens when not moving and can spread to both sides of the body8.
Bradykinesia (Slowed Movement)
Bradykinesia makes moving slow, making daily tasks hard7. It leads to a slow walk with small steps in most patients7. This includes slow movements, less facial expressions, and trouble with fine movements8.
Muscle Rigidity
Stiff muscles are common in Parkinson’s, causing painful muscle cramps for many7. It might be mistaken for arthritis early on8.
Impaired Posture and Balance
Later on, it can make keeping an upright posture hard and increase the chance of falling8. Walking gets harder, showing in small steps and shuffling8.
Changes in Speech and Writing
Changes in voice, like softening, are common in Parkinson’s8. Swallowing and drooling issues also happen8. Handwriting can become smaller and harder to read9.
But Parkinson’s isn’t just about motor symptoms. People may also face cognitive changes, depression, anxiety, and smell issues9. It’s important to manage these symptoms for better care and quality of life.
“Parkinson’s symptoms can vary among individuals and may change or progress differently for each person.”9
Causes and Risk Factors
The exact cause of Parkinson’s disease is still unknown, but it likely involves both genes and environment10. It affects about 1 million Americans10. Researchers are working hard to understand what triggers and worsens the disease.
Genetics and Environmental Triggers
Genetic changes can make someone more likely to get Parkinson’s, but this is rare, affecting only 10 to 20 percent of cases10. If you have a family history of the disease, your risk goes up10. But most cases don’t have a clear genetic cause.
Things like toxins, pesticides, and heavy metals might also cause Parkinson’s10. Being exposed to certain chemicals or having a history of head injuries could increase your risk10.
Parkinson’s is marked by the loss of brain cells that control movement11. This leads to a lack of dopamine, vital for movement and coordination12. Another neurotransmitter, norepinephrine, also plays a role in the disease’s symptoms12.
Some studies hint at a link between Parkinson’s and autoimmune diseases like rheumatoid arthritis12. This area is being closely studied as researchers try to understand how genetics, the immune system, and Parkinson’s interact.
While we can’t prevent Parkinson’s, living a healthy life might lower your risk12. Avoid toxins, protect your head, and exercise regularly to help.
“Parkinson’s disease is a complex condition, and we still have much to learn about the underlying causes and risk factors. However, ongoing research is providing valuable insights that may lead to more effective treatments and prevention strategies in the future.”
Diagnosis and Stages
Parkinson’s disease is a complex condition that’s hard to diagnose. There’s no single test to confirm it13. Doctors use a detailed medical history, a thorough neurological check, and symptom assessment to diagnose it13.
They look at symptoms like tremors, slow movements, stiff muscles, and unstable posture13. They also watch how the patient reacts to Parkinson’s medications. If symptoms get better, it could mean the patient has Parkinson’s13.
How Parkinson’s disease progresses can differ a lot from one person to another14. Some may see symptoms get worse slowly over years, while others may notice a quicker decline14. The disease goes through stages, from early to advanced, based on the Hoehn and Yahr scale14.
Doctors use scales like the Unified Parkinson’s Disease Rating Scale to check symptoms and track the disease’s progress14. These scales look at both movement and non-movement symptoms.
Some theories, like Braak’s Hypothesis, suggest Parkinson’s might start in the gut or nasal cavity and move to the brain14. This could link the disease’s start to an abnormal protein called α-Synuclein.
As we learn more about Parkinson’s, doctors and researchers are finding new ways to diagnose it. For example, the alpha-synuclein seed amplification assay is a promising new test15.
Managing Parkinson’s disease means creating a plan that fits the individual’s needs. Working with healthcare professionals helps people with Parkinson’s find the best treatments. This way, they can improve their quality of life and slow the disease’s progress15.
Parkinson’s Disease Treatment Options
There is no cure for Parkinson’s disease, but many treatments can help manage its symptoms. Medications like levodopa, dopamine agonists, and monoamine oxidase-B inhibitors increase dopamine levels or mimic its effects in the brain16. For some, deep brain stimulation, a surgery that implants electrodes in the brain, can control movement symptoms16. Physical, occupational, and speech therapy can also help improve gait, mobility, and communication17.
Medications
Levodopa is the top treatment for Parkinson’s symptoms17. But, it can cause nausea and tiredness16. Dopamine agonists may lead to nausea, confusion, and compulsive behaviors like gambling16. Monoamine oxidase-B inhibitors increase dopamine levels but can cause headaches and changes in blood pressure16. Catechol-O-Methyltransferase (COMT) inhibitors, used in later stages, may cause nausea and diarrhea16. Sometimes, apomorphine injections or continuous infusion pumps are used when tablets alone don’t control symptoms well16.
Deep Brain Stimulation
Surgeries like deep brain stimulation (DBS) and focused ultrasound (FUS) help some Parkinson’s patients17. They work best for those who respond well to levodopa and have no major cognitive or psychiatric issues17. Surgery can improve symptoms but doesn’t stop Parkinson’s from progressing18.
Physical, Occupational, and Speech Therapy
Physical therapy can make walking better for Parkinson’s patients17. Exercise can also help reduce and maybe slow Parkinson’s symptoms17. Occupational and speech therapy improve daily activities and communication17.
A team of specialists, including movement disorder specialists and rehabilitation experts, helps Parkinson’s patients17. Clinical trials are key to finding new treatments for Parkinson’s17.
“Finding the right medication and dosage for Parkinson’s disease may require time and patience, as every patient reacts differently to the available treatments.”18
In summary, while Parkinson’s has no cure, many treatments like medications, deep brain stimulation, and therapies can manage symptoms and improve life quality18.
Living with Parkinson’s Disease
As Parkinson’s disease gets worse, it makes daily tasks and social life harder19. But, with the right strategies and support, people with Parkinson’s can manage their symptoms and keep a good quality of life20.
Coping Strategies
Keeping a healthy lifestyle is key for those with Parkinson’s19. Regular exercise, like walking or Tai Chi, helps with mobility and balance19. Eating a diet full of fruits and veggies can ease constipation and boost health19.
Relaxation methods, like meditation, can also help with the physical and emotional side effects of Parkinson’s19. Adding these to daily life helps people cope with the disease and stay independent longer.
Support Groups and Resources
Support groups are very important for people with Parkinson’s, their families, and caregivers21. They offer a community where people can share stories, get advice, and find resources21. They also connect people with experts like Movement Disorder Specialists and Nurses19.
There are also national and local groups that provide help and info for those with Parkinson’s21. These resources cover everything from financial aid to staying active in the community.
Using coping strategies and support, people with Parkinson’s can adjust to their condition and keep their well-being20. With the right support and resources, they can live a full life and enjoy social activities20.
“Parkinson’s disease may change your life, but it doesn’t have to define it. With the right tools and support, you can learn to live well with this condition.”
Ongoing Research and Clinical Trials
Researchers are always looking for new ways to treat Parkinson’s disease. They’re exploring stem cell transplants and gene therapies. These methods aim to fix genetic issues and bring new dopamine-producing neurons to the brain22.
Even though these treatments aren’t yet widely used, they give hope for better managing and possibly curing Parkinson’s in the future22.
Studies with people are divided into two types: observational studies and clinical trials23. The biggest study on Parkinson’s is the Parkinson’s Foundation Parkinson’s Outcomes Project23.
Clinical trials go through phases to check safety, effectiveness, and how they compare to current treatments23. People in these trials help move forward with new treatments and care23.
Drugs, procedures, and therapies are tested by thousands of volunteers.23
- The “Rehabilitation of Airway Protection in Parkinson’s Disease” study looks at adults with Parkinson’s who have trouble swallowing and coughing22.
- At the University of Connecticut, researchers study how being active, feeling lonely, and making healthy choices affects people with Parkinson’s22.
- Researchers at the University of Nevada, Las Vegas, are looking into how Parkinson’s affects physical activity, mood, and thinking22.
- The University of Illinois Urbana-Champaign is studying speech in people with Parkinson’s22.
- Rebeca Higareda from New York University is studying how caregivers see voice changes in people with Parkinson’s22.
- The TOPAZ study is for people with Parkinson’s or similar conditions who are at risk of breaking bones22.
- The SPARX3 study by Northwestern Medicine looks at if treadmill exercise can help people with Parkinson’s22.
Research studies should come from trusted places like the Parkinson’s Foundation’s Centers of Excellence23.
Watch out for fake and misleading clinical trials that make big promises but hide the risks23.
24 Parkinson’s disease affects over 1 million people in the U.S. each year, with 60,000 new cases diagnosed yearly. The APDA has given over $170 million to research and patient services. Boston University has a big research program with 3500 patient visits a year and a fellowship in Movement Disorders. There are also many clinical trials for Parkinson’s disease at Boston University Medical Campus.
“Scientifically tested drugs, procedures, and therapies are likely to have been tested by thousands of volunteers.”
Prevention and Risk Reduction
Research suggests that certain lifestyle habits may help lower the risk of Parkinson’s disease25. Regular exercise, like brisk walking or cycling, can help prevent Parkinson’s26. Drinking caffeine, found in coffee, tea, and cola, might also slightly lower the risk26.
But, there’s no proven way to fully prevent Parkinson’s disease25. Avoiding toxins and pesticides might help, but we need more research25.
- Around 60% of people with Parkinson’s disease (PD) fall every year25.
- People with Parkinson’s who experience freezing episodes are at a higher risk of falling25.
- Medication side effects, including those prescribed for PD, can result in falls due to sleepiness and confusion25.
- PD symptoms can make it harder to keep moving, weakening leg and core muscles and impacting balance25.
- Parkinson’s can cause blurry or double vision and difficulty judging distances, affecting spatial awareness and balance25.
- If individuals depending on a mobility aid neglect to use it, they are at risk of falling25.
To lower the risk of falls25, regular exercise can help manage Parkinson’s and reduce falling chances25. Physical and occupational therapists offer personalized exercises for balance and mobility25. They might suggest using mobility aids like walking poles or canes for better stability25.
Home changes, such as removing tripping hazards and adding grab bars, can make the environment safer for people with Parkinson’s25. If someone falls, it’s important to stay calm, check for injuries, and plan before getting up25.
Preventing Parkinson’s disease is a big challenge, but managing symptoms and reducing fall risk can improve life quality25. By making lifestyle changes, exercising, and getting healthcare support, people with Parkinson’s can lessen the condition’s impact and keep their independence25.
“Parkinson’s disease is a complex and multifaceted condition, but there are steps we can take to reduce the risk and manage the symptoms. The key is to stay informed, proactive, and work closely with our healthcare team to develop a comprehensive plan that addresses our unique needs.”
Parkinson’s disease affects both men and women, but it’s 50% more common in men26. In the U.S., the disease’s prevalence increases from 1% at age 60 to 3% at age 8026. Exercise can prevent or delay Parkinson’s onset, and research shows that staying fit helps people with Parkinson’s perform better and live longer26. Eating a Mediterranean diet may also help lower blood pressure and reduce cardiovascular disease risk26.
Falls are a big concern for people with Parkinson’s, with studies showing a complex picture27. Guidelines for preventing and managing falls are crucial for older adults with Parkinson’s, marking a global effort27. Many people with Parkinson’s end up in the hospital due to falls, and using wearable sensors at home can help monitor and prevent falls27.
Research on Parkinson’s disease continues to be important in the medical field, with many studies published recently27. By keeping up with the latest research and advancements, individuals can take steps to protect their health and quality of life252627.
The Impact of Parkinson’s Disease
Parkinson’s disease can deeply affect a person’s daily life and overall happiness. It brings challenges with movement, speech, and other functions. It also changes how the brain works, making everyday tasks harder and affecting independence28.
Tremors are a common symptom that makes simple actions like writing or eating hard. The disease also slows down movements and makes muscles stiff. This makes doing even simple things tough29.
Changes in the brain can also affect memory, attention, and solving problems. In some cases, this can lead to Parkinson’s dementia, making it hard to live on your own28.
Despite these challenges, thanks to new treatments, most people with Parkinson’s can live a normal life span28. Yet, the daily effects of the disease can be big. Many struggle to stay independent and enjoy activities they loved before.
If Parkinson’s has touched you or someone close, finding support is key. Parkinson’s UK and other groups offer help with support groups, resources, and getting treatment and financial aid28.
| Parkinson’s Disease Impact | Statistics |
|---|---|
| Men are slightly more likely to get Parkinson’s disease than women. | 28 |
| Most people with Parkinson’s start to develop symptoms when they’re over 50, although some people with the condition first experience symptoms when they’re under 40. | 28 |
| An estimated 60,000 new cases of Parkinson’s disease are diagnosed annually. | 29 |
| Approximately one to 1.5 million Americans are currently living with Parkinson’s disease. | 29 |
| Falls are very common among individuals with Parkinson’s disease, largely due to balance issues and motor complications. | 30 |
Even with the big impact Parkinson’s has, there’s a lot of help and support out there. By understanding the symptoms, causes, and treatments, people with Parkinson’s can keep living well and independently for as long as they can.
“Parkinson’s disease is a journey, not a destination. With the right support and resources, individuals with Parkinson’s can continue to live fulfilling lives despite the challenges they face.”
If Parkinson’s is making life hard, don’t hesitate to ask for help. Contact Parkinson’s Association or Parkinson’s Association to find out about resources and support282930.
Caregiving and Support
Caring for someone with Parkinson’s disease is both challenging and rewarding. It requires a lot of effort, both physically and emotionally. In the U.S., Parkinson’s disease affects 500,000 to 1,500,000 people, with about 50,000 to 60,000 new cases each year31. Caregivers help with daily tasks, manage medicines, and support the person through physical and mental changes.
Dealing with Parkinson’s disease can be very stressful for caregivers. Up to 46% of them feel depressed or anxious32. About 75% of caregivers put their health at risk to care for their loved ones32. It’s important for caregivers to find support to keep their own well-being.
Support groups and services like respite care are very helpful for caregivers. They offer a break, emotional support, and practical help, easing the caregiving load32. Caregivers shouldn’t feel alone, as many organizations and communities support those caring for people with Parkinson’s disease.
With the right support, caregivers can handle the challenges of Parkinson’s disease better32. This leads to a better life for both the caregiver and the person with Parkinson’s, making their journey easier.
“Caring for a loved one with Parkinson’s disease is a labor of love, but it’s also a rollercoaster of emotions. With the right support, caregivers can find the strength to provide the best possible care while also taking care of themselves.”
Parkinson’s disease is known as a movement disorder caused by a loss of dopamine-producing cells in the brain33. Symptoms include tremors, stiff limbs, slow movements, and balance issues that get worse over time33. Other symptoms include sleep problems, urinary issues, constipation, swallowing difficulties, mood changes, and cognitive problems33.
For caregivers, tips include taking care of yourself, learning about the disease, getting help, dealing with depression, doing breathing exercises, and planning for the future33. It’s key for caregivers to ask for support and not feel overwhelmed by their responsibilities333132.
Raising Awareness and Advocacy
It’s vital to increase public awareness and advocacy for Parkinson’s disease. This helps improve the lives of those with this complex condition34. Advocacy efforts help get funding for new treatments and support for those with Parkinson’s and their caregivers34. By spreading the word and advocating, people can greatly help the Parkinson’s community.
Groups like the Michael J. Fox Foundation are leading the charge in Parkinson’s research and advocacy34. Recent breakthroughs, like finding a biomarker, have sped up research34. Even people without Parkinson’s can help by joining studies on smell loss and brain health34.
Advocacy groups push for policy changes related to Parkinson’s34. Events like the Parkinson’s Unity Walk in New York City raise money for research and support34. These efforts bring the community together to fight the disease.
In places like Africa, raising awareness is key because there’s little known about Parkinson’s and many believe it’s caused by witchcraft35. Advocacy is needed to improve care access and educate people about Parkinson’s35. Programs like SEE Parkinson’s and “the Spark” are helping African patients with Parkinson’s get support and learn more about their condition35.
By advocating for the Parkinson’s community, we can greatly improve lives34. With more research funding, support services, and understanding, we can look forward to a better future for those with Parkinson’s.
“Parkinson’s disease is the second most common neurodegenerative disease and the fastest growing neurological condition globally. The number of individuals affected by Parkinson’s disease is projected to reach 12.9 million by 2040, termed as the ‘Parkinson Pandemic.’”35
Conclusion
Parkinson’s disease is a complex condition that affects millions globally36. There’s no cure, but symptoms can be managed with treatments like medications, deep brain stimulation, and therapies37. Researchers are looking into new ways, like gene therapy and stem cell treatments, which could help in the future37.
The number of people with Parkinson’s is growing38. It’s important to spread awareness and support the Parkinson’s community. Helping those with the disease live well and enjoy life can make a big difference36.
Combining medical advances, tech, and support, the future for Parkinson’s patients is hopeful37. The challenges are big, but the Parkinson’s community’s strength and the hard work of researchers and healthcare workers give us hope. They lay the groundwork for better management of this complex condition.
FAQ
What is Parkinson’s disease?
What are the primary symptoms of Parkinson’s disease?
What causes Parkinson’s disease?
How is Parkinson’s disease diagnosed?
What treatments are available for Parkinson’s disease?
How can individuals with Parkinson’s disease cope with the disease?
What are some of the experimental treatments being explored for Parkinson’s disease?
Can Parkinson’s disease be prevented?
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Source Links
- Parkinson’s disease – Symptoms and causes – https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/symptoms-causes/syc-20376055
- Parkinson’s Disease: Causes, Symptoms, and Treatments – https://www.nia.nih.gov/health/parkinsons-disease/parkinsons-disease-causes-symptoms-and-treatments
- Parkinson’s Disease: What It Is, Causes, Symptoms & Treatment – https://my.clevelandclinic.org/health/diseases/8525-parkinsons-disease-an-overview
- What is Parkinson’s? – https://www.parkinson.org/understanding-parkinsons/what-is-parkinsons
- What is Parkinson’s Disease | APDA – https://www.apdaparkinson.org/what-is-parkinsons/
- Parkinson’s Disease – https://www.ninds.nih.gov/health-information/disorders/parkinsons-disease
- Parkinson’s disease – Symptoms – https://www.nhs.uk/conditions/parkinsons-disease/symptoms/
- Symptoms of Parkinson’s | APDA – https://www.apdaparkinson.org/what-is-parkinsons/symptoms/
- Parkinson’s symptoms – https://www.parkinsons.org.uk/information-and-support/parkinsons-symptoms
- Parkinson’s Disease Risk Factors and Causes – https://www.hopkinsmedicine.org/health/conditions-and-diseases/parkinsons-disease/parkinsons-disease-risk-factors-and-causes
- Parkinson’s disease – Causes – https://www.nhs.uk/conditions/parkinsons-disease/causes/
- Parkinson’s disease: Early signs, causes, and risk factors – https://www.medicalnewstoday.com/articles/323396
- How Parkinson’s Disease Is Diagnosed – https://www.hopkinsmedicine.org/health/treatment-tests-and-therapies/how-parkinson-disease-is-diagnosed
- Stages of Parkinson’s – https://www.parkinson.org/understanding-parkinsons/what-is-parkinsons/stages
- Parkinson’s disease – Diagnosis and treatment – Mayo Clinic – https://www.mayoclinic.org/diseases-conditions/parkinsons-disease/diagnosis-treatment/drc-20376062
- Parkinson’s disease – Treatment – https://www.nhs.uk/conditions/parkinsons-disease/treatment/
- Treatment & Medication | American Parkinson Disease Assoc. – https://www.apdaparkinson.org/what-is-parkinsons/treatment-medication/
- Parkinson’s Treatment Options – https://www.hopkinsmedicine.org/health/conditions-and-diseases/parkinsons-disease/parkinsons-treatment-options
- Living with Parkinson’s Disease | American Parkinson Disease Assoc. – https://www.apdaparkinson.org/resources-support/living-with-parkinsons-disease/
- Living With Parkinson’s Disease – https://www.ucsfhealth.org/education/living-with-parkinsons-disease
- Parkinson’s disease – Living with – https://www.nhs.uk/conditions/parkinsons-disease/living-with/
- Participate in a Clinical Trial | American Parkinson Disease Assoc. – https://www.apdaparkinson.org/research/clinical-trials/
- Clinical Trials – https://www.parkinson.org/living-with-parkinsons/treatment/clinical-trials
- Clinical Research | Parkinsons Disease & Movement Disorders Center – https://www.bumc.bu.edu/parkinsonsdisease/research/
- Fall Prevention in Parkinson’s – https://www.parkinson.org/library/fact-sheets/fall-prevention
- The Two Best Ways to Prevent Parkinsons Disease – https://www.umms.org/bwmc/news/2021/the-two-best-ways-to-prevent-parkinsons-disease
- Prevention of Falls in Parkinson’s Disease: Guidelines and Gaps – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585979/
- Parkinson’s disease – https://www.nhs.uk/conditions/parkinsons-disease/
- Parkinson’s Disease – https://www.aans.org/patients/conditions-treatments/parkinsons-disease/
- Parkinson’s Disease Impact On Quality of Life – https://www.parkinsonassociation.org/parkinsons-disease-impact-on-quality-of-life/
- Parkinson’s Disease and Caregiving – Family Caregiver Alliance – https://www.caregiver.org/resource/parkinsons-disease-caregiving/
- Coping Tips for Caregivers of Those With Parkinson’s Disease – https://www.webmd.com/parkinsons-disease/parkinsons-caregivers
- VA.gov | Veterans Affairs – https://www.caregiver.va.gov/Tips_by_Diagnosis/Parkinsons.asp
- Let’s Put an End to Parkinson’s. Together. – https://www.michaeljfox.org/parkinsons-awareness-month
- Parkinson’s Disease Awareness, Advocacy and Support Groups in Africa: Where are we Now? – https://www.movementdisorders.org/Moving-Along/PD-Africa
- Parkinson’s Disease: Challenges, Progress, and Promise – https://www.ninds.nih.gov/current-research/focus-disorders/parkinsons-disease-research/parkinsons-disease-challenges-progress-and-promise
- Case study (A and B): a patient with Parkinson’s disease – https://www.neuroscijournal.com/articles/jnnd-aid1073.php
- Parkinson’s Disease: Etiology, Neuropathology, and Pathogenesis – Parkinson’s Disease – https://www.ncbi.nlm.nih.gov/books/NBK536722/